Protein profile

VK055_1090

type VI secretion system protein

Genome: KpATCC43816

Gene: impH AIK79713.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GSH3
Export view
Amino acids 361
Annotations 0
Features 5
PDB binders 0
Druggability 0.658

Overview

Basic information about this protein and its source genome.

Accession
VK055_1090
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
impH AIK79713.1
Status
annotated
Amino acids
361
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
30.435
Localization
Unknown
ColabFold pLDDT
83.21

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.658
Structure A0A0H3GSH3
Pocket Pocket 13
P2Rank 0.067
Structure A0A0H3GSH3
Pocket Pocket 1
ColabFold model
FPocket 0.099 · Pocket 17
P2Rank 0.009 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 49 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
21 320 Pfam PF06996 Type VI secretion, TssG
21 320 InterPro IPR010732 Type VI secretion, TssG-like
21 320 NCBIfam TIGR03347 type VI secretion system baseplate subunit TssG
1 335 PANTHER PTHR35564 -
1 335 InterPro IPR010732 Type VI secretion, TssG-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GSH3
AlphaFold — — full sequence — Viewing
ColabFold VK055_1090
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
13 0.658
20 0.29
7 0.017
14 0.002

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.75 0.067
2 1.47 0.017
3 1.06 0.006