Protein profile

VK055_1091

type VI secretion system protein DUF879

Genome: KpATCC43816

Gene: impG AIK79714.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMD4
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Amino acids 584
Annotations 0
Features 7
PDB binders 0
Druggability 0.132

Overview

Basic information about this protein and its source genome.

Accession
VK055_1091
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
impG AIK79714.1
Status
annotated
Amino acids
584
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
26.959
Localization
Cytoplasmic
ColabFold pLDDT
84.29

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.132
Structure A0A0H3GMD4
Pocket Pocket 39
P2Rank 0.66
Structure A0A0H3GMD4
Pocket Pocket 1
ColabFold model
FPocket 0.191 · Pocket 54
P2Rank 0.503 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 62 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
6 581 NCBIfam TIGR03359 type VI secretion system baseplate subunit TssF
6 581 InterPro IPR010272 Type VI secretion system TssF
1 581 Pfam PF05947 Type VI secretion system, TssF
1 581 InterPro IPR010272 Type VI secretion system TssF
1 581 PANTHER PTHR35370 CYTOPLASMIC PROTEIN-RELATED-RELATED
1 583 PIRSF PIRSF028304 UCP028304
1 583 InterPro IPR010272 Type VI secretion system TssF

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMD4
AlphaFold — — full sequence — Viewing
ColabFold VK055_1091
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.22 0.438
2 3.81 0.148
3 1.58 0.025
4 1.54 0.023
5 1.05 0.006