Protein profile

VK055_1096

hypothetical protein

Genome: KpATCC43816

Gene: AIK79719.1 Structure source: AlphaFold + ColabFold UniProt A0A377ZUF0
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Amino acids 111
Annotations 0
Features 10
PDB binders 0
Druggability 0.301

Overview

Basic information about this protein and its source genome.

Accession
VK055_1096
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79719.1
Status
annotated
Amino acids
111
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
82.55

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.301
Structure A0A377ZUF0
Pocket Pocket 2
P2Rank 0.225
Structure A0A377ZUF0
Pocket Pocket 1
ColabFold model
FPocket 0.314 · Pocket 5
P2Rank 0.06 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 14 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 18 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
17 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
25 111 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
5 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
37 105 Pfam PF11745 Protein of unknown function (DUF3304)
37 105 InterPro IPR021733 Protein of unknown function DUF3304

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A377ZUF0
AlphaFold — — full sequence — Viewing
ColabFold VK055_1096
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.073
1 0.006
4 0.002
5 0.001

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.65 0.225