Protein profile

VK055_1150

phage shock protein A

Genome: KpATCC43816

Gene: AIK79773.1 pspA Structure source: AlphaFold + ColabFold UniProt A0A0H3GRR1
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Amino acids 222
Annotations 0
Features 10
PDB binders 0
Druggability 0.762

Overview

Basic information about this protein and its source genome.

Accession
VK055_1150
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79773.1 pspA
Status
annotated
Amino acids
222
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
59.174
DEG E-value
5.11e-86
Localization
CytoplasmicMembrane
ColabFold pLDDT
84.79

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.762
Structure A0A0H3GRR1
Pocket Pocket 7
P2Rank
Structure A0A0H3GRR1
Pocket No pockets
ColabFold model
FPocket 0.394 · Pocket 5
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 107 / 4744 genomes with a hit
Normalized 0.023

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
87 142 Coils Coil Coil
1 219 NCBIfam TIGR02977 phage shock protein PspA
1 219 InterPro IPR014319 Phage shock protein, PspA
47 81 Coils Coil Coil
2 216 Pfam PF04012 PspA/IM30 family
2 216 InterPro IPR007157 PspA/IM30
1 220 PANTHER PTHR31088 MEMBRANE-ASSOCIATED PROTEIN VIPP1, CHLOROPLASTIC
1 220 InterPro IPR007157 PspA/IM30
203 222 Coils Coil Coil
161 181 Coils Coil Coil

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GRR1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1150
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.762