Protein profile

VK055_1172

glycine zipper 2TM domain protein

Genome: KpATCC43816

Gene: AIK79795.1 Structure source: AlphaFold + ColabFold UniProt A6T7Z1
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Amino acids 46
Annotations 1
Features 2
PDB binders 0
Druggability 0.144

Overview

Basic information about this protein and its source genome.

Accession
VK055_1172
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79795.1
Status
annotated
Amino acids
46
Structure source
AlphaFold + ColabFold
GO
GO:0019867 The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
93.333
DEG E-value
6.61e-08
Localization
Unknown
ColabFold pLDDT
81.64

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.144
Structure A6T7Z1
Pocket Pocket 1
P2Rank
Structure A6T7Z1
Pocket No pockets
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 109 / 4744 genomes with a hit
Normalized 0.023

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0019867 The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.

Sequence Features

Domain/signature hits from InterPro and related databases.

2 records
Show feature table
Start End DB Term Name
7 45 Pfam PF05433 Glycine zipper 2TM domain
7 45 InterPro IPR008816 Glycine zipper 2TM domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A6T7Z1 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A6T7Z1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1172
ColabFold — — full sequence — Loaded