Protein profile

VK055_1490

phosphatidylethanolamine-binding family protein

Genome: KpATCC43816

Gene: AIK80110.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMH0
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Amino acids 184
Annotations 0
Features 19
PDB binders 0
Druggability 0.482

Overview

Basic information about this protein and its source genome.

Accession
VK055_1490
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80110.1
Status
annotated
Amino acids
184
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
31.356
Localization
Periplasmic
ColabFold pLDDT
93.8

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.482
Structure A0A0H3GMH0
Pocket Pocket 1
P2Rank 0.189
Structure A0A0H3GMH0
Pocket Pocket 1
ColabFold model
FPocket 0.474 · Pocket 1
P2Rank 0.267 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 112 / 4744 genomes with a hit
Normalized 0.024

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

19 records
Show feature table
Start End DB Term Name
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
8 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
24 180 SUPERFAMILY SSF49777 PEBP-like
24 180 InterPro IPR036610 PEBP-like superfamily
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 21 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
44 181 NCBIfam TIGR00481 YbhB/YbcL family Raf kinase inhibitor-like protein
44 181 InterPro IPR005247 YbhB/YbcL
49 180 Pfam PF01161 Phosphatidylethanolamine-binding protein
49 180 InterPro IPR008914 Phosphatidylethanolamine-binding protein
9 183 Gene3D G3DSA:3.90.280.10 -
9 183 InterPro IPR036610 PEBP-like superfamily
21 181 PANTHER PTHR30289 UNCHARACTERIZED PROTEIN YBCL-RELATED
21 181 InterPro IPR005247 YbhB/YbcL
22 184 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
25 181 CDD cd00865 PEBP_bact_arch
25 181 InterPro IPR005247 YbhB/YbcL
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMH0
AlphaFold — — full sequence — Viewing
ColabFold VK055_1490
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.001
3 0.0
6 0.0
8 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.04 0.189
2 4.59 0.163