Metabolic network

VK055_1542

tetraacyldisaccharide 4'-kinase

Network centrality 0.02952 top 93.7%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Lipopolysaccharide biosynthesis, no isoenzyme backup detected, more central than 93.7% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN2G6Z-1

EC 2.7.1.130 · RXN2G6Z-1 · not reversible · no isoenzyme backup

lipid A disaccharide (Vibrio cholerae serogroup O1 El Tor) ATP
lipid IVA (Vibrio cholerae serogroup O1 El Tor) ADP H+

RXN2B4Q-53

EC 2.7.1.130 · RXN2B4Q-53 · not reversible · no isoenzyme backup

dephospho-lipid IVA (Brucella) ATP
lipid IVA (Brucella) ADP H+

RXN2DNV-3

EC 2.7.1.130 · RXN2DNV-3 · not reversible · no isoenzyme backup

lipid A disaccharide (H. pylori) ATP
lipid IVA (H. pylori) ADP H+

RXN-20784

EC 2.7.1.130 · RXN-20784 · not reversible · no isoenzyme backup

Consuming chokepoint
lipid A disaccharide (P. putida) ATP
lipid IVA (P. putida) ADP H+

RXN-22238

EC 2.7.1.130 · RXN-22238 · not reversible · no isoenzyme backup

Producing & consuming chokepoint
lipid A disaccharide (P. gingivalis) ATP
lipid IVA (P. gingivalis) ADP H+

Imported from KpATCC43816.sbml · 2026-07-09