Protein profile

VK055_1624

hypothetical protein

Genome: KpATCC43816

Gene: AIK80244.1 Structure source: AlphaFold + ColabFold UniProt A0A483LD58
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Amino acids 102
Annotations 0
Features 7
PDB binders 0
Druggability 0.648

Overview

Basic information about this protein and its source genome.

Accession
VK055_1624
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80244.1
Status
annotated
Amino acids
102
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
53.846
DEG E-value
1.7999999999999998e-30
Localization
Unknown
ColabFold pLDDT
83.99

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.648
Structure A0A483LD58
Pocket Pocket 2
P2Rank
Structure A0A483LD58
Pocket No pockets
ColabFold model
FPocket 0.5 · Pocket 2
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 10 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
2 12 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
38 58 Coils Coil Coil
13 16 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 17 SignalP_EUK SignalP-noTM SignalP-noTM
1 16 Phobius SIGNAL_PEPTIDE Signal peptide region
17 102 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483LD58
AlphaFold — — full sequence — Viewing
ColabFold VK055_1624
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.648
6 0.038
1 0.0
7 0.0