Protein profile

VK055_1625

D-alanyl-D-alanine carboxypeptidase family protein

Genome: KpATCC43816

Gene: AIK80245.1 Structure source: AlphaFold + ColabFold UniProt A0A483L9E7
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Amino acids 113
Annotations 1
Features 6
PDB binders 0
Druggability 0.155

Overview

Basic information about this protein and its source genome.

Accession
VK055_1625
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80245.1
Status
annotated
Amino acids
113
Structure source
AlphaFold + ColabFold
GO
GO:0008233 Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
97.41

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.155
Structure A0A483L9E7
Pocket Pocket 2
P2Rank 0.728
Structure A0A483L9E7
Pocket Pocket 1
ColabFold model
FPocket 0.038 · Pocket 1
P2Rank 0.736 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 20 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0008233 Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
2 107 Gene3D G3DSA:3.30.1380.10 -
2 107 InterPro IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily
47 106 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase
47 106 InterPro IPR039561 Peptidase M15C
12 107 SUPERFAMILY SSF55166 Hedgehog/DD-peptidase
12 107 InterPro IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483L9E7
AlphaFold — — full sequence — Viewing
ColabFold VK055_1625
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.87 0.583
2 2.61 0.075