Protein profile

VK055_1632

phage small terminase subunit

Genome: KpATCC43816

Gene: AIK80252.1 Structure source: AlphaFold + ColabFold UniProt A0A483LHS1
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Amino acids 233
Annotations 3
Features 2
PDB binders 0
Druggability 0.394

Overview

Basic information about this protein and its source genome.

Accession
VK055_1632
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80252.1
Status
annotated
Amino acids
233
Structure source
AlphaFold + ColabFold
GO
GO:0004519 Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0019069 The assembly of a virus capsid from its protein subunits.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
94.8

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.394
Structure A0A483LHS1
Pocket Pocket 11
P2Rank 0.175
Structure A0A483LHS1
Pocket Pocket 1
ColabFold model
FPocket 0.327 · Pocket 1
P2Rank 0.141 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 15 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0004519 Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks.
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
  • GO:0019069 The assembly of a virus capsid from its protein subunits.

Sequence Features

Domain/signature hits from InterPro and related databases.

2 records
Show feature table
Start End DB Term Name
37 165 Pfam PF05944 Phage small terminase subunit
37 165 InterPro IPR010270 Bacteriophage P2, GpM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483LHS1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1632
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
11 0.394
1 0.006
2 0.0
5 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.8 0.175
2 1.41 0.015