Protein profile

VK055_1697

hypothetical protein

Genome: KpATCC43816

Gene: AIK80317.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQK4
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Amino acids 86
Annotations 1
Features 14
PDB binders 0
Druggability 0.011

Overview

Basic information about this protein and its source genome.

Accession
VK055_1697
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80317.1
Status
annotated
Amino acids
86
Structure source
AlphaFold + ColabFold
GO
GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
77.48

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.011
Structure A0A0H3GQK4
Pocket Pocket 3
P2Rank
Structure A0A0H3GQK4
Pocket No pockets
ColabFold model
FPocket 0.402 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 86 / 4744 genomes with a hit
Normalized 0.018

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 31 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
3 86 SUPERFAMILY SSF159871 YdgH-like
3 86 InterPro IPR036275 YdgH-like superfamily
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
1 86 PANTHER PTHR34156 OUTER MEMBRANE PROTEIN-RELATED-RELATED
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
22 86 Gene3D G3DSA:3.30.1660.10 -
22 86 InterPro IPR025543 Dodecin-like
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
19 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
34 86 Pfam PF07338 YdgH/BhsA/McbA-like domain
34 86 InterPro IPR010854 YdgH/BhsA/McbA-like domain
23 86 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQK4
AlphaFold — — full sequence — Viewing
ColabFold VK055_1697
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer