Metabolic network

VK055_2069

purE

Back to protein
Network centrality 0.02372 top 93.0%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing & consuming chokepoint reaction in Purine metabolism, no isoenzyme backup detected, more central than 93.0% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Purine metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

Select a node
EC
-
Pathway
-
Genes
-
Role
-
Isoenzymes
-

Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN0-743

EC 5.4.99.18 · RXN0-743 · not reversible · no isoenzyme backup

Producing & consuming chokepoint
N5-carboxyaminoimidazole ribonucleotide
→
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

Imported from KpATCC43816.sbml · 2026-07-09