Metabolic network

VK055_2367

acetyl-CoA carboxylase, carboxyl transferase, alpha subunit

Back to protein
Network centrality 0.14188 top 98.3%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Aflatoxin biosynthesis, more central than 98.3% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Aflatoxin biosynthesis Fatty acid biosynthesis Mycolic acid biosynthesis Other carbon fixation pathways Propanoate metabolism Pyruvate metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN0-5055

EC 2.1.3.15 · RXN0-5055 · not reversible · 3 isoenzymes

Consuming chokepoint
acetyl-CoA a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine
→
malonyl-CoA a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine

BIOTIN-CARBOXYL-RXN

EC 6.3.4.14 · BIOTIN-CARBOXYL-RXN · not reversible · 3 isoenzymes

Producing & consuming chokepoint
a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine hydrogen carbonate ATP
→
phosphate a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine ADP H+

Imported from KpATCC43816.sbml · 2026-07-09