Metabolic network

VK055_2477

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

Back to protein
Network centrality 0.07003 top 96.6%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Peptidoglycan biosynthesis, no isoenzyme backup detected, more central than 96.6% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Peptidoglycan biosynthesis

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-11029

EC 2.4.1.227 · RXN-11029 · reversible · no isoenzyme backup

Dec-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UDP-N-acetyl-alpha-D-glucosamine
⇌
H+ Dec-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UDP

NACGLCTRANS-RXN

EC 2.4.1.227 · NACGLCTRANS-RXN · not reversible · no isoenzyme backup

Und-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UDP-N-acetyl-alpha-D-glucosamine
→
H+ Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UDP

RXN-11346

EC 2.4.1.227 · RXN-11346 · reversible · no isoenzyme backup

Und-PP-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala UDP-N-acetyl-alpha-D-glucosamine
⇌
H+ Und-PP-beta-D-GlcNAc-(1->4)-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala UDP

RXN-8976

EC 2.4.1.227 · RXN-8976 · reversible · no isoenzyme backup

Und-PP-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala UDP-N-acetyl-alpha-D-glucosamine
⇌
H+ Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala UDP

RXN-22611

EC 2.4.1.227 · RXN-22611 · not reversible · no isoenzyme backup

Consuming chokepoint
Und-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Lac UDP-N-acetyl-alpha-D-glucosamine
→
Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Lac UDP H+

Imported from KpATCC43816.sbml · 2026-07-09