KEGG:map00550

Peptidoglycan biosynthesis

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 13
Proteins 10
Metabolites 32
Chokepoints 8

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 16 shared KEGG Amino sugar and nucleotide sugar metabolism 6 shared KEGG Terpenoid backbone biosynthesis 2 shared KEGG D-Amino acid metabolism 2 shared KEGG Lysine biosynthesis 1 shared KEGG Lipopolysaccharide biosynthesis 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

6.3.2.10-RXN

EC 6.3.2.10 · R04573 · 6.3.2.10-RXN · not reversible

D-alanyl-D-alanine UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine ATP
→
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine ADP H+ phosphate
VK055_2482

NACGLCTRANS-RXN

EC 2.4.1.227 · R05032 · NACGLCTRANS-RXN · not reversible

UDP-N-acetyl-alpha-D-glucosamine Und-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala
→
Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala H+ UDP
VK055_2477

PHOSNACMURPENTATRANS-RXN

EC 2.7.8.13 · R05630 · PHOSNACMURPENTATRANS-RXN · not reversible

producing
UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala di-trans,octa-cis-undecaprenyl phosphate
→
Und-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UMP
VK055_2481

RXN-8975

EC 2.7.8.13 · R05629 · RXN-8975 · not reversible

consuming
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine di-trans,octa-cis-undecaprenyl phosphate
→
Und-PP-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala UMP
VK055_2481

RXN-8976

EC 2.4.1.227 · R05662 · RXN-8976 · reversible

UDP-N-acetyl-alpha-D-glucosamine Und-PP-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala
⇌
Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala H+ UDP
VK055_2477

RXN-8999

EC 2.5.1.31 · R06447 · RXN-8999 · not reversible

(2E,6E)-farnesyl diphosphate isopentenyl diphosphate
→
di-trans,octa-cis-undecaprenyl diphosphate diphosphate
VK055_2378

UDP-NACMURALA-GLU-LIG-RXN

EC 6.3.2.9 · R02783 · UDP-NACMURALA-GLU-LIG-RXN · not reversible

both
D-glutamate UDP-N-acetyl-alpha-D-muramoyl-L-alanine ATP
→
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate ADP H+ phosphate
VK055_2480

UDP-NACMUR-ALA-LIG-RXN

EC 6.3.2.8 · R03193 · UDP-NACMUR-ALA-LIG-RXN · not reversible

producing
L-alanine UDP-N-acetyl-alpha-D-muramate ATP
→
UDP-N-acetyl-alpha-D-muramoyl-L-alanine ADP H+ phosphate
VK055_2476

UDP-NACMURALGLDAPAALIG-RXN

EC 6.3.2.10 · R04617 · UDP-NACMURALGLDAPAALIG-RXN · not reversible

D-alanyl-D-alanine UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP ATP
→
UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala ADP H+ phosphate
VK055_2482

UDP-NACMURALGLDAPLIG-RXN

EC 6.3.2.13 · R02788 · UDP-NACMURALGLDAPLIG-RXN · not reversible

consuming
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate meso-diaminopimelate ATP
→
UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP ADP H+ phosphate
VK055_2483