Metabolic network

VK055_2593

thymidine phosphorylase

Network centrality 0.01019 top 90.5%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Pyrimidine metabolism, more central than 90.5% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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EC
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Pathway
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-25247

EC 2.4.2.2 · RXN-25247 · not reversible · 2 isoenzymes

trifluridine phosphate
trifluorothymine 2-deoxy-alpha-D-ribose 1-phosphate

THYM-PHOSPH-RXN

EC 2.4.2.2, 2.4.2.4 · THYM-PHOSPH-RXN · reversible · no isoenzyme backup

phosphate thymidine
thymine 2-deoxy-alpha-D-ribose 1-phosphate

RXN-25225

EC 2.4.2.2 · RXN-25225 · not reversible · 2 isoenzymes

doxifluridine phosphate
5-fluorouracil 2-deoxy-alpha-D-ribose 1-phosphate

URA-PHOSPH-RXN

EC 2.4.2.2, 2.4.2.3 · URA-PHOSPH-RXN · not reversible · 2 isoenzymes

Consuming chokepoint
2'-deoxyuridine phosphate
uracil 2-deoxy-alpha-D-ribose 1-phosphate

Imported from KpATCC43816.sbml · 2026-07-09