KEGG:map00240

Pyrimidine metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 41
Proteins 27
Metabolites 54
Chokepoints 15

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 91 shared KEGG Purine metabolism 18 shared KEGG Glycerophospholipid metabolism 9 shared KEGG Pentose phosphate pathway 8 shared KEGG Arginine biosynthesis 5 shared KEGG Galactose metabolism 5 shared KEGG Pentose and glucuronate interconversions 5 shared KEGG Pantothenate and CoA biosynthesis 4 shared KEGG Terpenoid backbone biosynthesis 4 shared KEGG Glycine, serine and threonine metabolism 3 shared KEGG Biosynthesis of various nucleotide sugars 3 shared KEGG Citrate cycle (TCA cycle) 2 shared KEGG Lipopolysaccharide biosynthesis 2 shared KEGG Cysteine and methionine metabolism 2 shared KEGG Amino sugar and nucleotide sugar metabolism 2 shared KEGG One carbon pool by folate 2 shared KEGG Histidine metabolism 2 shared KEGG Alanine, aspartate and glutamate metabolism 2 shared KEGG Phenylalanine metabolism 1 shared KEGG Tyrosine metabolism 1 shared KEGG Valine, leucine and isoleucine degradation 1 shared KEGG Nitrogen metabolism 1 shared KEGG Glyoxylate and dicarboxylate metabolism 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

CTPSYN-RXN

EC 6.3.4.2 · R00573 · CTPSYN-RXN · not reversible

L-glutamine ATP H2O UTP
→
L-glutamate ADP CTP H+ phosphate
VK055_4390

CYTIDEAM-RXN

EC 3.5.4.5 · R02485 · CYTIDEAM-RXN · not reversible

producing
2'-deoxycytidine H+ H2O
→
2'-deoxyuridine ammonium
VK055_4939

OROPRIBTRANS-RXN

EC 2.4.2.10 · R01870 · OROPRIBTRANS-RXN · not reversible

both
5-phospho-alpha-D-ribose 1-diphosphate orotate
→
orotidine 5'-phosphate diphosphate
VK055_3486

RXN-12195

EC 3.6.1.15 · R00569 · RXN-12195 · not reversible

CTP H2O
→
CDP H+ phosphate
No mapped protein

RXN-12196

EC 3.6.1.15 · R00159 · RXN-12196 · not reversible

H2O UTP
→
H+ UDP phosphate
No mapped protein

RXN-12197

EC 3.6.1.6 · R00155 · RXN-12197 · not reversible

H2O UDP
→
H+ UMP phosphate
No mapped protein

RXN-12198

EC 3.6.1.6 · R00514 · RXN-12198 · not reversible

CDP H2O
→
CMP H+ phosphate
No mapped protein

RXN-7913

EC 2.7.4.13, 2.7.4.14, 2.7.4.25 · R01665 · RXN-7913 · not reversible

consuming
dCMP ATP
→
dCDP ADP
VK055_1547

THYM-PHOSPH-RXN

EC 2.4.2.2, 2.4.2.4 · R01570 · THYM-PHOSPH-RXN · reversible

thymidine phosphate
⇌
2-deoxy-alpha-D-ribose 1-phosphate thymine
VK055_2593

URPHOS-RXN

EC 2.4.2.2, 2.4.2.3 · R01876 · URPHOS-RXN · not reversible

uridine phosphate
→
alpha-D-ribose-1-phosphate uracil
VK055_3149