Protein profile

VK055_2702

hypothetical protein

Genome: KpATCC43816

Gene: AIK81292.1 Structure source: Experimental + ColabFold UniProt A0A0H3GLZ1
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Amino acids 88
Annotations 1
Features 7
PDB binders 0
Druggability 0.73

Overview

Basic information about this protein and its source genome.

Accession
VK055_2702
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81292.1
Status
annotated
Amino acids
88
Structure source
Experimental + ColabFold
GO
GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
34.483
Localization
Unknown
ColabFold pLDDT
92.68

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.73
Structure 5ZGN
Pocket Pocket 1
P2Rank
Structure 5ZGN
Pocket No pockets
ColabFold model
FPocket 0.882 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 24 / 4744 genomes with a hit
Normalized 0.005

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
3 88 Gene3D G3DSA:1.20.5.780 Single helix bin
8 86 Pfam PF08681 Protein of unknown function (DUF1778)
8 86 InterPro IPR014795 Vibrio phage ICP1, Orf50
2 86 PANTHER PTHR35401 COPG FAMILY HELIX-TURN-HELIX PROTEIN-RELATED-RELATED
2 86 InterPro IPR014795 Vibrio phage ICP1, Orf50
5 82 SUPERFAMILY SSF47598 Ribbon-helix-helix
5 82 InterPro IPR010985 Ribbon-helix-helix

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 5ZGN
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
ColabFold VK055_2702
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
43 0.229

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.68 0.339
2 6.37 0.321
3 3.86 0.151
4 3.11 0.105
5 2.7 0.08