Protein profile

VK055_2738

putative atpase involved in dna repair

Genome: KpATCC43816

Gene: AIK81328.1 Structure source: AlphaFold + ColabFold UniProt A0A483I469
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Amino acids 1213
Annotations 0
Features 9
PDB binders 0
Druggability 0.268

Overview

Basic information about this protein and its source genome.

Accession
VK055_2738
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81328.1
Status
annotated
Amino acids
1213
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
86.41

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.268
Structure A0A483I469
Pocket Pocket 14
P2Rank 0.895
Structure A0A483I469
Pocket Pocket 1
ColabFold model
FPocket 0.302 · Pocket 53
P2Rank 0.541 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 4 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1186 1206 Coils Coil Coil
2 1200 NCBIfam NF033441 BREX system P-loop protein BrxC
2 1200 InterPro IPR047679 BREX system P-loop protein BrxC
212 1142 PANTHER PTHR18976 APOLIPOPROTEIN
62 305 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
62 305 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
524 567 Coils Coil Coil
1112 1149 Coils Coil Coil
1035 1074 Coils Coil Coil

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483I469
AlphaFold — — full sequence — Viewing
ColabFold VK055_2738
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
14 0.268
90 0.237

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.32 0.555
2 8.24 0.439
3 7.99 0.425
4 2.47 0.068
5 2.41 0.064