Protein profile

VK055_2762

prophage CP4-57 regulatory family protein

Genome: KpATCC43816

Gene: AIK81352.1 Structure source: AlphaFold + ColabFold UniProt A0A422ZFY9
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Amino acids 67
Annotations 0
Features 4
PDB binders 0
Druggability 0.069

Overview

Basic information about this protein and its source genome.

Accession
VK055_2762
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81352.1
Status
annotated
Amino acids
67
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
48.387
DEG E-value
4.32e-15
Localization
Unknown
ColabFold pLDDT
93.07

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.069
Structure A0A422ZFY9
Pocket Pocket 1
P2Rank
Structure A0A422ZFY9
Pocket No pockets
ColabFold model
FPocket 0.647 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 40 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
4 57 PANTHER PTHR36154 DNA-BINDING TRANSCRIPTIONAL ACTIVATOR ALPA
6 55 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA)
6 55 InterPro IPR010260 DNA-binding transcriptional activator AlpA
6 63 Gene3D G3DSA:1.10.238.160 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A422ZFY9
AlphaFold — — full sequence — Viewing
ColabFold VK055_2762
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer