Network centrality
0.32068
top 99.4%
Chokepoint
Yes
Attractive metabolic target: catalyzes a consuming chokepoint reaction in Inositol phosphate metabolism, no isoenzyme backup detected, more central than 99.4% of genes in this genome.
Pathways
KEGG pathways this gene's reaction(s) belong to.
Network
Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.
Reaction catalyzed by this protein
Chokepoint reaction
Neighbor reaction
Pathway grouping (2+ reactions sharing a route)
Connected reaction (arrow shows direction, when known)
⇌ Reversible reaction (double arrow)
Cross-pathway connection
Selected reaction
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Catalyzed reactions
Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.
1.2.1.27-RXN
EC 1.2.1.27 · 1.2.1.27-RXN · reversible · no isoenzyme backup
methylmalonate semialdehyde
coenzyme A
NAD+
H2O
⇌
propanoyl-CoA
hydrogen carbonate
NADH
H+
3-oxopropanoate
coenzyme A
NAD+
→
acetyl-CoA
CO2
NADH
Imported from KpATCC43816.sbml · 2026-07-09