KEGG:map00280

Valine, leucine and isoleucine degradation

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 13
Proteins 7
Metabolites 33
Chokepoints 1

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

1.2.1.27-RXN

EC 1.2.1.27 · R00922 · 1.2.1.27-RXN · reversible

methylmalonate semialdehyde H2O NAD+ coenzyme A
hydrogen carbonate propanoyl-CoA H+ NADH

2.3.1.168-RXN

EC 2.3.1.168 · R02662 · 2.3.1.168-RXN · reversible

an [apo BCAA dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine isobutanoyl-CoA
an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine coenzyme A
No mapped protein

2.6.1.22-RXN

EC 2.6.1.22 · R04188 · 2.6.1.22-RXN · reversible

(S)-3-amino-2-methylpropanoate 2-oxoglutarate
(S)-methylmalonate-semialdehyde L-glutamate
No mapped protein

3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN

EC 3.1.2.4 · R05064 · 3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN · not reversible

(S)-3-hydroxy-isobutanoyl-CoA H2O
(S)-3-hydroxy-isobutanoate H+ coenzyme A
No mapped protein

MEPROPCOA-FAD-RXN

EC 1.3.8.5 · R02661 · MEPROPCOA-FAD-RXN · not reversible

an oxidized electron-transfer flavoprotein isobutanoyl-CoA H+
a reduced electron-transfer flavoprotein methylacrylyl-CoA
No mapped protein

METHYLACYLYLCOA-HYDROXY-RXN

EC 4.2.1.150 · R04224 · METHYLACYLYLCOA-HYDROXY-RXN · reversible

(S)-3-hydroxy-isobutanoyl-CoA
methylacrylyl-CoA H2O
No mapped protein

METHYLMALONYL-COA-EPIM-RXN

EC 5.1.99.1 · R02765 · METHYLMALONYL-COA-EPIM-RXN · not reversible

(R)-methylmalonyl-CoA
(S)-methylmalonyl-CoA
No mapped protein