Protein profile

VK055_3009

hypothetical protein

Genome: KpATCC43816

Gene: AIK81594.1 Structure source: AlphaFold + ColabFold UniProt A0A377XI89
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Amino acids 78
Annotations 0
Features 12
PDB binders 0
Druggability 0.666

Overview

Basic information about this protein and its source genome.

Accession
VK055_3009
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81594.1
Status
annotated
Amino acids
78
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
67.55

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.666
Structure A0A377XI89
Pocket Pocket 2
P2Rank
Structure A0A377XI89
Pocket No pockets
ColabFold model
FPocket 0.961 · Pocket 8
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 64 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
10 13 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 75 Pfam PF15940 Family of unknown function
1 75 InterPro IPR016958 Uncharacterised conserved protein UCP030798
1 78 PIRSF PIRSF030798 UCP030798
1 78 InterPro IPR016958 Uncharacterised conserved protein UCP030798
1 1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
23 49 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 13 Phobius SIGNAL_PEPTIDE Signal peptide region
21 43 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
50 78 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
2 9 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
14 22 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A377XI89
AlphaFold — — full sequence — Viewing
ColabFold VK055_3009
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.112
4 0.052
1 0.02
6 0.004