Metabolic network

VK055_3340

UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase

Back to protein
Network centrality 0.10556 top 97.6%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Amino sugar and nucleotide sugar metabolism, no isoenzyme backup detected, more central than 97.6% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Amino sugar and nucleotide sugar metabolism Biosynthesis of various nucleotide sugars

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

2.3.1.157-RXN

EC 2.3.1.157 · 2.3.1.157-RXN · not reversible · no isoenzyme backup

Producing chokepoint
acetyl-CoA alpha-D-glucosamine 1-phosphate
→
N-acetyl-alpha-D-glucosamine 1-phosphate coenzyme A H+

NAG1P-URIDYLTRANS-RXN

EC 2.7.7.23 · NAG1P-URIDYLTRANS-RXN · not reversible · no isoenzyme backup

Consuming chokepoint
UTP N-acetyl-alpha-D-glucosamine 1-phosphate H+
→
UDP-N-acetyl-alpha-D-glucosamine diphosphate

Imported from KpATCC43816.sbml · 2026-07-09