KEGG:map00541

Biosynthesis of various nucleotide sugars

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 25
Proteins 20
Metabolites 56
Chokepoints 15

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 23 shared KEGG Pentose phosphate pathway 4 shared KEGG Glycolysis / Gluconeogenesis 3 shared KEGG Pyrimidine metabolism 3 shared KEGG One carbon pool by folate 2 shared KEGG Glycine, serine and threonine metabolism 2 shared KEGG Glyoxylate and dicarboxylate metabolism 2 shared KEGG Streptomycin biosynthesis 2 shared KEGG Lipopolysaccharide biosynthesis 2 shared KEGG Pentose and glucuronate interconversions 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

5.1.3.20-RXN

EC 5.1.3.20 · R05176 · 5.1.3.20-RXN · not reversible

both
ADP-D-glycero-beta-D-manno-heptose
→
ADP-L-glycero-beta-D-manno-heptose
VK055_3508

CPM-KDOSYNTH-RXN

EC 2.7.7.38 · R03351 · CPM-KDOSYNTH-RXN · not reversible

producing
3-deoxy-alpha-D-manno-2-octulosonate CTP
→
CMP-3-deoxy-beta-D-manno-octulosonate diphosphate
VK055_1539

DTDPDEHYDRHAMEPIM-RXN

EC 5.1.3.13 · R06514 · DTDPDEHYDRHAMEPIM-RXN · not reversible

dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose
→
dTDP-4-dehydro-beta-L-rhamnose
No mapped protein

DTDPGLUCDEHYDRAT-RXN

EC 4.2.1.46 · R06513 · DTDPGLUCDEHYDRAT-RXN · not reversible

consuming
dTDP-alpha-D-glucose
→
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose H2O
VK055_3187

KDO-8PPHOSPHAT-RXN

EC 3.1.3.45 · R03350 · KDO-8PPHOSPHAT-RXN · not reversible

consuming
3-deoxy-D-manno-octulosonate 8-phosphate H2O
→
3-deoxy-alpha-D-manno-2-octulosonate phosphate
VK055_3869

KDO-8PSYNTH-RXN

EC 2.5.1.55 · R03254 · KDO-8PSYNTH-RXN · not reversible

producing
D-arabinofuranose 5-phosphate phosphoenolpyruvate H2O
→
3-deoxy-D-manno-octulosonate 8-phosphate phosphate
VK055_0220

NAG1P-URIDYLTRANS-RXN

EC 2.7.7.23 · R00416 · NAG1P-URIDYLTRANS-RXN · not reversible

consuming
N-acetyl-alpha-D-glucosamine 1-phosphate H+ UTP
→
UDP-N-acetyl-alpha-D-glucosamine diphosphate
VK055_3340

NANK-RXN

EC 2.7.1.60 · R02705 · NANK-RXN · not reversible

N-acetyl-D-mannosamine ATP
→
N-acetyl-D-mannosamine 6-phosphate ADP H+
No mapped protein

RFFTRANS-RXN

EC 2.6.1.59 · R04438 · RFFTRANS-RXN · reversible

2-oxoglutarate dTDP-4-amino-4,6-dideoxy-alpha-D-galactose
⇌
L-glutamate dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose
No mapped protein

RXN0-1861

EC 1.1.1.305 · R07658 · RXN0-1861 · not reversible

producing
UDP-alpha-D-glucuronate NAD+
→
UDP-beta-L-threo-pentapyranos-4-ulose CO2 NADH
VK055_3625

RXN0-1862

EC 2.1.2.13 · R07660 · RXN0-1862 · not reversible

both
UDP-4-amino-4-deoxy-beta-L-arabinopyranose an N10-formyltetrahydrofolate
→
UDP-4-deoxy-4-formamido-beta-L-arabinopyranose a tetrahydrofolate H+
VK055_3625

RXN0-1863

EC 2.6.1.87, 2.6.1.92 · R07659 · RXN0-1863 · not reversible

both
L-glutamate UDP-beta-L-threo-pentapyranos-4-ulose
→
2-oxoglutarate UDP-4-amino-4-deoxy-beta-L-arabinopyranose
VK055_3623

RXN0-3521

EC 2.4.2.53 · R07661 · RXN0-3521 · not reversible

both
UDP-4-deoxy-4-formamido-beta-L-arabinopyranose di-trans,octa-cis-undecaprenyl phosphate
→
4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate UDP
VK055_3624

RXN0-4341

EC 2.7.1.167 · R05646 · RXN0-4341 · not reversible

D-glycero-D-manno-heptose 7-phosphate ATP
→
D-glycero-beta-D-manno-heptose 1,7-bisphosphate ADP H+
No mapped protein

RXN0-4342

EC 2.7.7.70 · R05644 · RXN0-4342 · not reversible

D-glycero-beta-D-manno-heptose 1-phosphate ATP H+
→
ADP-D-glycero-beta-D-manno-heptose diphosphate
No mapped protein

RXN0-4361

EC 3.1.3.82 · R05647 · RXN0-4361 · not reversible

both
D-glycero-beta-D-manno-heptose 1,7-bisphosphate H2O
→
D-glycero-beta-D-manno-heptose 1-phosphate phosphate
VK055_2352

RXN0-5409

EC - · R07662 · RXN0-5409 · not reversible

4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate H2O
→
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate formate
No mapped protein

TDPFUCACTRANS-RXN

EC 2.3.1.210 · R10142 · TDPFUCACTRANS-RXN · not reversible

producing
acetyl-CoA dTDP-4-amino-4,6-dideoxy-alpha-D-galactose
→
dTDP-4-acetamido-alpha-D-fucose H+ coenzyme A
VK055_3185