KDOTRANS-RXN
EC 2.4.99.12 · KDOTRANS-RXN · not reversible · no isoenzyme backup
Network centrality
0.03876
top 94.7%
Chokepoint
Yes
Attractive metabolic target: catalyzes a consuming chokepoint reaction in Lipopolysaccharide biosynthesis, no isoenzyme backup detected, more central than 94.7% of genes in this genome, no human homolog detected.
Pathways
KEGG pathways this gene's reaction(s) belong to.
Network
Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.
Reaction catalyzed by this protein
Chokepoint reaction
Neighbor reaction
Pathway grouping (2+ reactions sharing a route)
Connected reaction (arrow shows direction, when known)
⇌ Reversible reaction (double arrow)
Cross-pathway connection
Selected reaction
Click a node in the network above, or a row in the table below, to inspect it here.
Select a node
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- Isoenzymes
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Catalyzed reactions
Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.
RXN2DNV-4
EC 2.4.99.12 · RXN2DNV-4 · not reversible · no isoenzyme backup
CMP-3-deoxy-beta-D-manno-octulosonate
lipid IVA (H. pylori)
→
alpha-Kdo-(2->6)-lipid IVA (H. pylori)
CMP
H+
RXN2DNV-5
EC 2.4.99.13 · RXN2DNV-5 · not reversible · no isoenzyme backup
CMP-3-deoxy-beta-D-manno-octulosonate
alpha-Kdo-(2->6)-lipid IVA (H. pylori)
→
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (H. pylori)
CMP
H+
RXN-22249
EC 2.4.99.13 · RXN-22249 · not reversible · no isoenzyme backup
CMP-3-deoxy-beta-D-manno-octulosonate
alpha-Kdo-(2->6)-lipid IVA (P. gingivalis)
→
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (P. gingivalis)
CMP
H+
RXN-22248
EC 2.4.99.12 · RXN-22248 · not reversible · no isoenzyme backup
CMP-3-deoxy-beta-D-manno-octulosonate
lipid IVA (P. gingivalis)
→
alpha-Kdo-(2->6)-lipid IVA (P. gingivalis)
CMP
H+
Imported from KpATCC43816.sbml · 2026-07-09