Protein profile

VK055_3732

osmC-like family protein

Genome: KpATCC43816

Gene: AIK82287.1 Structure source: AlphaFold + ColabFold UniProt A0A377YUF9
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Amino acids 110
Annotations 0
Features 8
PDB binders 0
Druggability 0.248

Overview

Basic information about this protein and its source genome.

Accession
VK055_3732
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82287.1
Status
annotated
Amino acids
110
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
55.14
DEG E-value
1.42e-41
Localization
Unknown
ColabFold pLDDT
95.35

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.248
Structure A0A377YUF9
Pocket Pocket 4
P2Rank
Structure A0A377YUF9
Pocket No pockets
ColabFold model
FPocket 0.561 · Pocket 9
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 147 / 4744 genomes with a hit
Normalized 0.031

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
6 103 Pfam PF02566 OsmC-like protein
6 103 InterPro IPR003718 OsmC/Ohr family
11 110 Gene3D G3DSA:3.30.300.20 -
11 110 InterPro IPR015946 K homology domain-like, alpha/beta
4 108 PANTHER PTHR34352 PROTEIN YHFA
15 32 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 109 SUPERFAMILY SSF82784 OsmC-like
1 109 InterPro IPR036102 OsmC/Ohr superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A377YUF9
AlphaFold — — full sequence — Viewing
ColabFold VK055_3732
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.248