Protein profile

VK055_3895

yfaZ family protein

Genome: KpATCC43816

Gene: AIK82444.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GTQ6
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Amino acids 115
Annotations 0
Features 5
PDB binders 0
Druggability 0.129

Overview

Basic information about this protein and its source genome.

Accession
VK055_3895
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82444.1
Status
annotated
Amino acids
115
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
89.11

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.129
Structure A0A0H3GTQ6
Pocket Pocket 1
P2Rank 0.105
Structure A0A0H3GTQ6
Pocket Pocket 1
ColabFold model
FPocket 0.391 · Pocket 2
P2Rank 0.048 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 76 / 4744 genomes with a hit
Normalized 0.016

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
5 115 Gene3D G3DSA:2.40.160.20 -
1 115 Pfam PF07437 YfaZ precursor
1 115 InterPro IPR009998 YfaZ
2 115 SUPERFAMILY SSF56925 OMPA-like
2 115 InterPro IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GTQ6
AlphaFold — — full sequence — Viewing
ColabFold VK055_3895
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.54 0.071