Protein profile

VK055_3923

hypothetical protein

Genome: KpATCC43816

Gene: AIK82471.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GYV0
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Amino acids 128
Annotations 1
Features 12
PDB binders 0
Druggability 0.058

Overview

Basic information about this protein and its source genome.

Accession
VK055_3923
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82471.1
Status
annotated
Amino acids
128
Structure source
AlphaFold + ColabFold
GO
GO:0003676 Binding to a nucleic acid.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
86.23

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.058
Structure A0A0H3GYV0
Pocket Pocket 5
P2Rank 0.216
Structure A0A0H3GYV0
Pocket Pocket 1
ColabFold model
FPocket 0.2 · Pocket 3
P2Rank 0.108 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 111 / 4744 genomes with a hit
Normalized 0.023

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
16 123 SUPERFAMILY SSF52980 Restriction endonuclease-like
16 123 InterPro IPR011335 Restriction endonuclease type II-like
18 95 CDD cd20736 PoNe_Nuclease
15 127 Hamap MF_00048 UPF0102 protein YraN [yraN].
15 127 InterPro IPR003509 UPF0102 protein YraN-like
22 128 Gene3D G3DSA:3.40.1350.10 -
22 128 InterPro IPR011856 tRNA endonuclease-like domain superfamily
23 113 Pfam PF02021 Uncharacterised protein family UPF0102
23 113 InterPro IPR003509 UPF0102 protein YraN-like
15 127 PANTHER PTHR34039 UPF0102 PROTEIN YRAN
15 126 NCBIfam TIGR00252 YraN family protein
15 126 InterPro IPR003509 UPF0102 protein YraN-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GYV0
AlphaFold — — full sequence — Viewing
ColabFold VK055_3923
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.95 0.095