Protein profile

VK055_3942

hypothetical protein

Genome: KpATCC43816

Gene: AIK82490.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GXX3
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Amino acids 101
Annotations 2
Features 13
PDB binders 0
Druggability 0.605

Overview

Basic information about this protein and its source genome.

Accession
VK055_3942
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82490.1
Status
annotated
Amino acids
101
Structure source
AlphaFold + ColabFold
GO
GO:0043022 Binding to a ribosome. GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
75.8

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.605
Structure A0A0H3GXX3
Pocket Pocket 7
P2Rank
Structure A0A0H3GXX3
Pocket No pockets
ColabFold model
FPocket 0.358 · Pocket 6
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 104 / 4744 genomes with a hit
Normalized 0.022

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0043022 Binding to a ribosome.
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
7 27 Coils Coil Coil
29 49 Coils Coil Coil
81 99 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
2 101 PANTHER PTHR35893 INNER MEMBRANE PROTEIN-RELATED
2 101 InterPro IPR010279 Inner membrane protein YqjD/ElaB
26 50 MobiDBLite mobidb-lite consensus disorder prediction
72 101 Pfam PF19029 DUF883 C-terminal glycine zipper region
72 101 InterPro IPR043605 DUF883, C-terminal domain
8 60 Pfam PF05957 DUF883 N-terminal domain
8 60 InterPro IPR043604 DUF883, N-terminal domain
1 80 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
81 98 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
100 101 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GXX3
AlphaFold — — full sequence — Viewing
ColabFold VK055_3942
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
8 0.445
2 0.034
3 0.026
4 0.002