Protein profile

VK055_3988

hypothetical protein

Genome: KpATCC43816

Gene: AIK82536.1 Structure source: Experimental + ColabFold UniProt A6TE93
Export view
Amino acids 223
Annotations 0
Features 11
PDB binders 0
Druggability 0.634

Overview

Basic information about this protein and its source genome.

Accession
VK055_3988
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82536.1
Status
annotated
Amino acids
223
Structure source
Experimental + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
56.938
DEG E-value
4.78e-79
Localization
Periplasmic
ColabFold pLDDT
80.4

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.634
Structure 3DZA
Pocket Pocket 1
P2Rank 0.042
Structure 3DZA
Pocket Pocket 1
ColabFold model
FPocket 0.536 · Pocket 11
P2Rank 0.029 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 16 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
43 126 Gene3D G3DSA:1.20.120.1940 YfdX protein domain
14 22 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
32 223 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 31 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
23 31 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
127 183 Gene3D G3DSA:6.10.250.2140 -
1 13 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 31 Phobius SIGNAL_PEPTIDE Signal peptide region
1 31 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
67 218 Pfam PF10938 YfdX protein
67 218 InterPro IPR021236 Uncharacterised protein family YfdX

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 3DZA
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
ColabFold VK055_3988
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.968
3 0.778
16 0.634
2 0.259

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 13.53 0.69
2 11.91 0.631
3 11.3 0.605
4 10.58 0.568
5 5.96 0.293