Protein profile

VK055_4018

glycogen synthesis family protein

Genome: KpATCC43816

Gene: AIK82565.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GYK7
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Amino acids 65
Annotations 2
Features 8
PDB binders 0
Druggability 0.318

Overview

Basic information about this protein and its source genome.

Accession
VK055_4018
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82565.1
Status
annotated
Amino acids
65
Structure source
AlphaFold + ColabFold
GO
GO:1902201 Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility. GO:1900191 Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
74.55

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.318
Structure A0A0H3GYK7
Pocket Pocket 1
P2Rank 0.028
Structure A0A0H3GYK7
Pocket Pocket 1
ColabFold model
FPocket 0.246 · Pocket 2
P2Rank 0.019 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 44 / 4744 genomes with a hit
Normalized 0.009

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:1902201 Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.
  • GO:1900191 Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
3 59 Pfam PF08971 Glycogen synthesis protein
3 59 InterPro IPR015065 Surface composition regulator
1 60 Hamap MF_00525 Surface composition regulator [glgS].
1 60 InterPro IPR015065 Surface composition regulator
3 59 SUPERFAMILY SSF109747 Glycogen synthesis protein GlgS
3 59 InterPro IPR036295 GlgS superfamily
1 65 Gene3D G3DSA:1.20.970.20 Glycogen synthesis protein GlgS
1 65 InterPro IPR036295 GlgS superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GYK7
AlphaFold — — full sequence — Viewing
ColabFold VK055_4018
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.318
5 0.004
7 0.001
10 0.001

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.8 0.028
2 1.22 0.01
3 1.11 0.007