Protein profile

VK055_4091

hypothetical protein

Genome: KpATCC43816

Gene: AIK82637.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GT56
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Amino acids 96
Annotations 1
Features 14
PDB binders 0
Druggability 0.184

Overview

Basic information about this protein and its source genome.

Accession
VK055_4091
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82637.1
Status
annotated
Amino acids
96
Structure source
AlphaFold + ColabFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
34.211
Human E-value
5.93e-11
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
85.35

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.184
Structure A0A0H3GT56
Pocket Pocket 6
P2Rank 0.007
Structure A0A0H3GT56
Pocket Pocket 1
ColabFold model
FPocket 0.208 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 127 / 4744 genomes with a hit
Normalized 0.027

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
7 83 SMART SM01152 DUF167_2
7 83 InterPro IPR003746 Protein of unknown function DUF167
10 81 Pfam PF02594 Uncharacterised ACR, YggU family COG1872
10 81 InterPro IPR003746 Protein of unknown function DUF167
10 87 PANTHER PTHR13420 UNCHARACTERIZED
10 87 InterPro IPR003746 Protein of unknown function DUF167
4 92 SUPERFAMILY SSF69786 YggU-like
4 92 InterPro IPR036591 YggU-like superfamily
1 96 Gene3D G3DSA:3.30.1200.10 -
1 96 InterPro IPR036591 YggU-like superfamily
7 93 Hamap MF_00634 UPF0235 protein YggU [yggU].
7 93 InterPro IPR003746 Protein of unknown function DUF167
12 81 NCBIfam TIGR00251 DUF167 family protein
12 81 InterPro IPR003746 Protein of unknown function DUF167

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GT56
AlphaFold — — full sequence — Viewing
ColabFold VK055_4091
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.19 0.01