Metabolic network

VK055_4099

glutathione synthase

Network centrality 0
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Glutathione metabolism, no isoenzyme backup detected, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-20407

EC 6.3.2.3 · RXN-20407 · not reversible · no isoenzyme backup

glycine gamma-L-glutamyl-L-alanine ATP
norophthalmate ADP phosphate H+

RXN-20401

EC 6.3.2.3 · RXN-20401 · not reversible · no isoenzyme backup

glycine gamma-L-glutamyl-(S)-2-aminobutanoate ATP
ophthalmate ADP phosphate H+

GLUTATHIONE-SYN-RXN

EC 6.3.2.3 · GLUTATHIONE-SYN-RXN · not reversible · no isoenzyme backup

Consuming chokepoint
glycine gamma-L-glutamyl-L-cysteine ATP
glutathione ADP phosphate H+

Imported from KpATCC43816.sbml · 2026-07-09