KEGG:map00480

Glutathione metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 10
Proteins 8
Metabolites 28
Chokepoints 4

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 18 shared KEGG Citrate cycle (TCA cycle) 2 shared KEGG Glyoxylate and dicarboxylate metabolism 1 shared KEGG Selenocompound metabolism 1 shared KEGG Histidine metabolism 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

1.11.1.12-RXN

EC 1.11.1.12 · R03167 · 1.11.1.12-RXN · not reversible

a hydroperoxy-fatty-acyl-[lipid] glutathione
→
a hydroxy-fatty-acyl-[lipid] glutathione disulfide H2O
No mapped protein

GLU6PDEHYDROG-RXN

EC 1.1.1.49 · R02736 · GLU6PDEHYDROG-RXN · not reversible

producing
D-glucopyranose 6-phosphate NADP+
→
6-phospho D-glucono-1,5-lactone H+ NADPH
VK055_0081

GLUTATHIONE-SYN-RXN

EC 6.3.2.3 · R00497 · GLUTATHIONE-SYN-RXN · not reversible

consuming
gamma-L-glutamyl-L-cysteine glycine ATP
→
glutathione ADP H+ phosphate
VK055_4099

GLUTCYSLIG-RXN

EC 6.3.2.2 · R00894 · GLUTCYSLIG-RXN · not reversible

producing
L-cysteine L-glutamate ATP
→
gamma-L-glutamyl-L-cysteine ADP H+ phosphate
VK055_4497

RXN-9952

EC 1.1.1.44 · R01528 · RXN-9952 · not reversible

D-gluconate 6-phosphate NADP+
→
D-ribulose 5-phosphate CO2 NADPH
VK055_5026

SPERMIDINESYN-RXN

EC 2.5.1.16 · R01920 · SPERMIDINESYN-RXN · not reversible

both
S-adenosyl 3-(methylsulfanyl)propylamine putrescine
→
S-methyl-5'-thioadenosine spermidine H+
VK055_2442