Protein profile

VK055_4117

cupin domain protein

Genome: KpATCC43816

Gene: AIK82663.1 Structure source: ColabFold
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Amino acids 158
Annotations 0
Features 8
PDB binders 0
Druggability 0.869

Overview

Basic information about this protein and its source genome.

Accession
VK055_4117
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82663.1
Status
annotated
Amino acids
158
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
95.27

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.869
Structure CB_VK055_4117
Pocket Pocket 1
P2Rank 0.787
Structure CB_VK055_4117
Pocket Pocket 1
ColabFold model
FPocket 0.869 · Pocket 1
P2Rank 0.787 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 37 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
28 152 SUPERFAMILY SSF51182 RmlC-like cupins
28 152 InterPro IPR011051 RmlC-like cupin domain superfamily
24 158 Gene3D G3DSA:2.60.120.10 Jelly Rolls
24 158 InterPro IPR014710 RmlC-like jelly roll fold
6 157 CDD cd02225 cupin_PA3510-like
65 132 Pfam PF07883 Cupin domain
65 132 InterPro IPR013096 Cupin 2, conserved barrel
8 137 PANTHER PTHR43346 LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_4117
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.869

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 12.76 0.661
2 1.6 0.025