Protein profile

VK055_4181

papC C-terminal domain protein

Genome: KpATCC43816

Gene: AIK82726.1 Structure source: ColabFold

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Amino acids 55

Annotations 0

Features 4

PDB binders 0

Druggability 0.025

Overview

Basic information about this protein and its source genome.

Accession: VK055_4181
Assembly: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene: AIK82726.1
Status: annotated
Amino acids: 55
Structure source: ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Human identity (%): 0.0
Gut microbiome off-target: hit
Essential (DEG): Y
DEG identity (%): 46.154
DEG E-value: 1.54e-06
Localization: Unknown
ColabFold pLDDT: 85.83

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.025

Structure CB_VK055_4181

Pocket Pocket 1

P2Rank 0.035

Structure CB_VK055_4181

Pocket Pocket 1

ColabFold model

FPocket 0.025 · Pocket 1

P2Rank 0.035 · Pocket 1

Core conservation Accessory gene

Roary accessory

CoreCruncher accessory

Gut microbiome 4 / 4744 genomes with a hit

Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records

Show feature table

Start	End	DB	Term	Name
2	37	Pfam	PF13953	PapC C-terminal domain
2	37	InterPro	IPR025949	PapC-like, C-terminal domain
1	55	Gene3D	G3DSA:2.60.40.2070	-
1	55	InterPro	IPR043142	PapC-like, C-terminal domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
ColabFold VK055_4181	ColabFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK	Sticks	Spheres	Surfaces	Score	Probability	Labels	Zoom	Positions
1				2.9	0.092