Metabolic network

VK055_4310

cob(I)alamin adenosyltransferase

Network centrality 0.03998 top 94.8%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Porphyrin metabolism, more central than 94.8% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-19366

EC - · RXN-19366 · not reversible · 3 isoenzymes

adenosylcob(III)alamin-[corrinoid adenosyltranferase]
adenosylcobalamin a [corrinoid adenosyltransferase]

RXN-19340

EC - · RXN-19340 · not reversible · 3 isoenzymes

cob(II)alamin a [corrinoid adenosyltransferase]
cob(II)alamin-[corrinoid adenosyltranferase]

R344-RXN

EC - · R344-RXN · not reversible · 3 isoenzymes

2 ATP 2 cob(I)yrinate a,c-diamide-[corrinoid adenosyltranferase] 2 H+
2 adenosyl-cob(III)yrinate a,c-diamide 2 triphosphate 2 a [corrinoid adenosyltransferase]

RXN-19342

EC - · RXN-19342 · not reversible · 3 isoenzymes

cob(II)inamide a [corrinoid adenosyltransferase]
[corrinoid adenosyltranferase]-cob(II)inamide

RXN-19344

EC - · RXN-19344 · not reversible · 3 isoenzymes

Producing chokepoint
cob(II)yrinate a,c-diamide a [corrinoid adenosyltransferase]
cob(II)yrinate a,c-diamide-[corrinoid adenosyltranferase]

RXN-19343

EC - · RXN-19343 · not reversible · 3 isoenzymes

Consuming chokepoint
2 ATP 2 [corrinoid adenosyltranferase]-cob(I)inamide 2 H+
2 adenosylcobinamide 2 triphosphate 2 a [corrinoid adenosyltransferase]

COBALADENOSYLTRANS-RXN

EC - · COBALADENOSYLTRANS-RXN · not reversible · 3 isoenzymes

Producing & consuming chokepoint
cob(I)alamin-[corrinoid adenosyltranferase] ATP H+
adenosylcob(III)alamin-[corrinoid adenosyltranferase] triphosphate

Imported from KpATCC43816.sbml · 2026-07-09