Protein profile

VK055_4486

recX family protein

Genome: KpATCC43816

Gene: AIK83029.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H1V2
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Amino acids 166
Annotations 2
Features 13
PDB binders 0
Druggability 0.194

Overview

Basic information about this protein and its source genome.

Accession
VK055_4486
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83029.1
Status
annotated
Amino acids
166
Structure source
AlphaFold + ColabFold
GO
GO:0006282 Any process that modulates the frequency, rate or extent of DNA repair. GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
31.884
Localization
Cytoplasmic
ColabFold pLDDT
91.33

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.194
Structure A0A0H3H1V2
Pocket Pocket 3
P2Rank
Structure A0A0H3H1V2
Pocket No pockets
ColabFold model
FPocket 0.394 · Pocket 9
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 69 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0006282 Any process that modulates the frequency, rate or extent of DNA repair.
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
116 166 Gene3D G3DSA:1.10.10.10 -
116 166 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
8 69 Gene3D G3DSA:1.10.10.10 -
8 69 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
5 163 PANTHER PTHR33602 REGULATORY PROTEIN RECX FAMILY PROTEIN
5 163 InterPro IPR003783 Regulatory protein RecX
70 115 Gene3D G3DSA:1.10.10.10 -
70 115 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
70 115 FunFam G3DSA:1.10.10.10:FF:000134 Regulatory protein RecX
10 166 Hamap MF_01114 Regulatory protein RecX [recX].
10 166 InterPro IPR003783 Regulatory protein RecX
50 162 Pfam PF02631 RecX family
50 162 InterPro IPR003783 Regulatory protein RecX

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H1V2
AlphaFold — — full sequence — Viewing
ColabFold VK055_4486
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer