Protein profile

VK055_4488

global regulator family protein

Genome: KpATCC43816

Gene: AIK83031.1 Structure source: ColabFold
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Amino acids 37
Annotations 3
Features 8
PDB binders 0
Druggability 0.068

Overview

Basic information about this protein and its source genome.

Accession
VK055_4488
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83031.1
Status
annotated
Amino acids
37
Structure source
ColabFold
GO
GO:0006109 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. GO:0003723 Binding to an RNA molecule or a portion thereof. GO:0006402 The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
97.297
DEG E-value
7.82e-21
Localization
Unknown
ColabFold pLDDT
83.61

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.068
Structure CB_VK055_4488
Pocket Pocket 1
P2Rank
Structure CB_VK055_4488
Pocket No pockets
ColabFold model
FPocket 0.068 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 272 / 4744 genomes with a hit
Normalized 0.057

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0006109 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
  • GO:0003723 Binding to an RNA molecule or a portion thereof.
  • GO:0006402 The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 37 Gene3D G3DSA:2.60.40.4380 Translational regulator CsrA
1 37 InterPro IPR036107 Carbon storage regulator superfamily
2 28 Pfam PF02599 Global regulator protein family
2 28 InterPro IPR003751 Translational regulator CsrA
2 30 SUPERFAMILY SSF117130 CsrA-like
2 30 InterPro IPR036107 Carbon storage regulator superfamily
1 36 PANTHER PTHR34984 CARBON STORAGE REGULATOR
1 36 InterPro IPR003751 Translational regulator CsrA

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed ColabFold model VK055_4488 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_4488
ColabFold — — full sequence — Viewing