Protein profile

VK055_4516

hypothetical protein

Genome: KpATCC43816

Gene: AIK83054.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GWH9
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Amino acids 115
Annotations 2
Features 11
PDB binders 0
Druggability 0.17

Overview

Basic information about this protein and its source genome.

Accession
VK055_4516
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83054.1
Status
annotated
Amino acids
115
Structure source
AlphaFold + ColabFold
GO
GO:0043022 Binding to a ribosome. GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
67.96

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.17
Structure A0A0H3GWH9
Pocket Pocket 2
P2Rank
Structure A0A0H3GWH9
Pocket No pockets
ColabFold model
FPocket 0.096 · Pocket 11
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 63 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0043022 Binding to a ribosome.
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
15 63 Pfam PF05957 DUF883 N-terminal domain
15 63 InterPro IPR043604 DUF883, N-terminal domain
40 60 Coils Coil Coil
3 114 PANTHER PTHR35893 INNER MEMBRANE PROTEIN-RELATED
3 114 InterPro IPR010279 Inner membrane protein YqjD/ElaB
85 114 Pfam PF19029 DUF883 C-terminal glycine zipper region
85 114 InterPro IPR043605 DUF883, C-terminal domain
1 93 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
94 113 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
114 115 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
94 113 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GWH9 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GWH9
AlphaFold — — full sequence — Viewing
ColabFold VK055_4516
ColabFold — — full sequence — Loaded