Protein profile

VK055_4530

fimbrial family protein

Genome: KpATCC43816

Gene: AIK83068.1 Structure source: AlphaFold + ColabFold UniProt W1DS60
Export view
Amino acids 173
Annotations 3
Features 8
PDB binders 0
Druggability 0.073

Overview

Basic information about this protein and its source genome.

Accession
VK055_4530
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83068.1
Status
annotated
Amino acids
173
Structure source
AlphaFold + ColabFold
GO
GO:0007155 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289 A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709 The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
31.646
Localization
Extracellular
ColabFold pLDDT
80.78

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.073
Structure W1DS60
Pocket Pocket 6
P2Rank 0.624
Structure W1DS60
Pocket Pocket 1
ColabFold model
FPocket 0.13 · Pocket 1
P2Rank 0.559 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 15 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0007155 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
  • GO:0009289 A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.
  • GO:0043709 The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
17 173 PANTHER PTHR33420 FIMBRIAL SUBUNIT ELFA-RELATED
24 173 SUPERFAMILY SSF49401 Bacterial adhesins
24 173 InterPro IPR008966 Adhesion domain superfamily
20 172 Gene3D G3DSA:2.60.40.1090 -
20 172 InterPro IPR036937 Fimbrial-type adhesion domain superfamily
1 22 MobiDBLite mobidb-lite consensus disorder prediction
25 172 Pfam PF00419 Fimbrial protein
25 172 InterPro IPR000259 Fimbrial-type adhesion domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W1DS60
AlphaFold — — full sequence — Viewing
ColabFold VK055_4530
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 9.92 0.533
2 3.11 0.105