Protein profile

VK055_4550

transcriptional regulator family protein

Genome: KpATCC43816

Gene: AIK83088.1 Structure source: ColabFold
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Amino acids 142
Annotations 0
Features 10
PDB binders 0
Druggability 0.81

Overview

Basic information about this protein and its source genome.

Accession
VK055_4550
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83088.1
Status
annotated
Amino acids
142
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
87.74

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.81
Structure CB_VK055_4550
Pocket Pocket 5
P2Rank 0.622
Structure CB_VK055_4550
Pocket Pocket 1
ColabFold model
FPocket 0.81 · Pocket 5
P2Rank 0.622 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 37 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
3 118 SUPERFAMILY SSF46785 Winged helix DNA-binding domain
3 118 InterPro IPR036390 Winged helix DNA-binding domain superfamily
1 124 PANTHER PTHR33221 WINGED HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, RRF2 FAMILY
1 124 InterPro IPR000944 Transcription regulator Rrf2
1 118 ProSiteProfiles PS51197 Rrf2-type HTH domain profile.
1 118 InterPro IPR000944 Transcription regulator Rrf2
3 117 Pfam PF02082 Iron-dependent Transcriptional regulator
3 117 InterPro IPR000944 Transcription regulator Rrf2
1 127 Gene3D G3DSA:1.10.10.10 -
1 127 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_4550
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.81
11 0.209

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.11 0.369
2 2.98 0.097