Protein profile

VK055_4554

flavin reductase domain protein, FMN-binding protein

Genome: KpATCC43816

Gene: AIK83092.1 Structure source: ColabFold
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Amino acids 190
Annotations 1
Features 8
PDB binders 0
Druggability 0.187

Overview

Basic information about this protein and its source genome.

Accession
VK055_4554
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83092.1
Status
annotated
Amino acids
190
Structure source
ColabFold
GO
GO:0010181 Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
96.0

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.187
Structure CB_VK055_4554
Pocket Pocket 2
P2Rank 0.214
Structure CB_VK055_4554
Pocket Pocket 1
ColabFold model
FPocket 0.187 · Pocket 2
P2Rank 0.214 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 11 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0010181 Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 182 Gene3D G3DSA:2.30.110.10 -
1 182 InterPro IPR012349 FMN-binding split barrel
14 151 SMART SM00903 Flavin_Reduct_2
14 151 InterPro IPR002563 Flavin reductase like domain
10 180 PANTHER PTHR43567 FLAVOREDOXIN-RELATED-RELATED
47 148 Pfam PF01613 Flavin reductase like domain
47 148 InterPro IPR002563 Flavin reductase like domain
2 178 SUPERFAMILY SSF50475 FMN-binding split barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_4554
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.93 0.039