Protein profile

VK055_4631

PRD domain protein

Genome: KpATCC43816

Gene: AIK83166.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GTR2
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Amino acids 425
Annotations 1
Features 8
PDB binders 0
Druggability 0.282

Overview

Basic information about this protein and its source genome.

Accession
VK055_4631
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83166.1
Status
annotated
Amino acids
425
Structure source
AlphaFold + ColabFold
GO
GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
90.32

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.282
Structure A0A0H3GTR2
Pocket Pocket 7
P2Rank 0.791
Structure A0A0H3GTR2
Pocket Pocket 1
ColabFold model
FPocket 0.545 · Pocket 24
P2Rank 0.722 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 67 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
235 329 Gene3D G3DSA:1.10.1790.10 PRD domain
11 424 PANTHER PTHR30185 CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR
234 332 SUPERFAMILY SSF63520 PTS-regulatory domain, PRD
234 332 InterPro IPR036634 PRD domain superfamily
229 336 ProSiteProfiles PS51372 PRD domain profile.
229 336 InterPro IPR011608 PRD domain
241 328 Pfam PF00874 PRD domain
241 328 InterPro IPR011608 PRD domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GTR2
AlphaFold — — full sequence — Viewing
ColabFold VK055_4631
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
28 0.03
1 0.004
35 0.002
33 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 20.25 0.791
2 3.2 0.088
3 2.5 0.056
4 2.19 0.043
5 1.99 0.035