Protein profile

VK055_4676

SEC-C motif family protein

Genome: KpATCC43816

Gene: AIK83210.1 Structure source: ColabFold
Amino acids 792
Annotations 0
Features 4
PDB binders 0
Druggability 0.87

Overview

Basic information about this protein and its source genome.

Accession
VK055_4676
Gene
AIK83210.1
Status
annotated
Amino acids
792
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
82.609
Localization
Cytoplasmic
ColabFold pLDDT
88.18

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.87
Structure CB_VK055_4676
Pocket Pocket 4
P2Rank 0.608
Structure CB_VK055_4676
Pocket Pocket 1
ColabFold model
FPocket 0.87 · Pocket 4
P2Rank 0.608 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 1 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
774 792 Pfam PF02810 SEC-C motif
774 792 InterPro IPR004027 SEC-C motif
683 792 Gene3D G3DSA:3.10.450.50 -
771 791 SUPERFAMILY SSF103642 Sec-C motif

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_4676
ColabFold full sequence Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.87
57 0.78
55 0.46
23 0.273

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.45 0.325
2 6.3 0.316
3 4.03 0.161
4 2.43 0.066
5 1.75 0.032