Protein profile

VK055_4723

ethanolamine utilization protein EutJ

Genome: KpATCC43816

Gene: eutJ AIK83257.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GWH0
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Amino acids 279
Annotations 0
Features 12
PDB binders 0
Druggability 0.966

Overview

Basic information about this protein and its source genome.

Accession
VK055_4723
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
eutJ AIK83257.1
Status
annotated
Amino acids
279
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
30.909
Localization
Cytoplasmic
ColabFold pLDDT
91.62

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.966
Structure A0A0H3GWH0
Pocket Pocket 1
P2Rank 0.937
Structure A0A0H3GWH0
Pocket Pocket 1
ColabFold model
FPocket 0.609 · Pocket 4
P2Rank 0.947 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 29 / 4744 genomes with a hit
Normalized 0.006

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
141 245 Pfam PF11104 Type IV pilus assembly protein PilM;
141 245 InterPro IPR005883 Type IV pilus inner membrane component PilM
142 259 SUPERFAMILY SSF53067 Actin-like ATPase domain
142 259 InterPro IPR043129 ATPase, nucleotide binding domain
141 253 Gene3D G3DSA:3.30.420.40 -
33 164 CDD cd00012 NBD_sugar-kinase_HSP70_actin
31 266 Gene3D G3DSA:3.30.420.40 -
31 132 SUPERFAMILY SSF53067 Actin-like ATPase domain
31 132 InterPro IPR043129 ATPase, nucleotide binding domain
34 267 NCBIfam TIGR02529 ethanolamine utilization protein EutJ family protein
34 267 InterPro IPR013366 Ethanolamine utilisation EutJ
27 104 PANTHER PTHR32432 CELL DIVISION PROTEIN FTSA-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GWH0
AlphaFold — — full sequence — Viewing
ColabFold VK055_4723
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.966

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 22.35 0.88
2 1.87 0.037
3 1.49 0.021