Protein profile

VK055_4830

yfbU domain protein

Genome: KpATCC43816

Gene: AIK83357.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GR64
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Amino acids 164
Annotations 0
Features 10
PDB binders 0
Druggability 0.12

Overview

Basic information about this protein and its source genome.

Accession
VK055_4830
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83357.1
Status
annotated
Amino acids
164
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
95.23

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.12
Structure A0A0H3GR64
Pocket Pocket 1
P2Rank 0.167
Structure A0A0H3GR64
Pocket Pocket 1
ColabFold model
FPocket 0.359 · Pocket 10
P2Rank 0.136 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 119 / 4744 genomes with a hit
Normalized 0.025

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
53 164 FunFam G3DSA:1.10.3190.10:FF:000001 UPF0304 protein YfbU
53 164 Gene3D G3DSA:1.10.3190.10 yfbu gene product, domain 2
53 164 InterPro IPR023146 YfbU, alpha-helical bundle domain superfamily
1 164 PIRSF PIRSF006272 UCP006272
1 164 InterPro IPR005587 Uncharacterised protein family UPF0304, YfbU
1 164 Pfam PF03887 YfbU domain
1 50 Gene3D G3DSA:1.10.287.680 Helix hairpin bin
1 50 InterPro IPR023145 YfbU, helix-hairpin domain superfamily
1 164 SUPERFAMILY SSF116960 YfbU-like
1 164 Hamap MF_00762 UPF0304 protein YfbU [yfbU].

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GR64
AlphaFold — — full sequence — Viewing
ColabFold VK055_4830
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.88 0.037
2 1.26 0.012