Metabolic network

VK055_4939

cytidine deaminase

Back to protein
Network centrality 0.25724 top 99.2%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Pyrimidine metabolism, no isoenzyme backup detected, more central than 99.2% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Pyrimidine metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-25236

EC 3.5.4.5 · RXN-25236 · not reversible · no isoenzyme backup

gemcitabine H2O H+
→
2', 2'-difluorodeoxyuridine ammonium

CYTIDEAM-RXN

EC 3.5.4.5 · CYTIDEAM-RXN · not reversible · no isoenzyme backup

Producing chokepoint
H+ H2O 2'-deoxycytidine
→
2'-deoxyuridine ammonium

Imported from KpATCC43816.sbml · 2026-07-09