Metabolic network

VK055_4975

hydroxyethylthiazole kinase

Back to protein
Network centrality 0
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Thiamine metabolism, no isoenzyme backup detected, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Thiamine metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-23965

EC 2.7.1.50 · RXN-23965 · not reversible · no isoenzyme backup

ATP 5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-carboxylate
→
2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate ADP H+

THIAZOLSYN3-RXN

EC 2.7.1.50 · THIAZOLSYN3-RXN · not reversible · no isoenzyme backup

Producing chokepoint
ATP 5-(2-hydroxyethyl)-4-methylthiazole
→
H+ ADP 4-methyl-5-(2-phosphooxyethyl)thiazole

Imported from KpATCC43816.sbml · 2026-07-09